Asked by Baroness Meacher To ask Her Majesty's Government
whether they plan to invite the Advisory Council on the Misuse of
Drugs to review the evidence supporting the rescheduling of
cannabis to Schedule 2 or 4. Baroness Meacher (CB) My Lords,
chronically sick patients with constant severe pain and other
symptoms have suffered for far too long,...Request free trial
Asked by
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To ask Her Majesty's Government whether they plan to invite
the Advisory Council on the Misuse of Drugs to review the
evidence supporting the rescheduling of cannabis to
Schedule 2 or 4.
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(CB)
My Lords, chronically sick patients with constant severe
pain and other symptoms have suffered for far too long,
reliant on prescribed medications that are sometimes
ineffective and with intolerable side-effects for many
people.
I remind noble Lords, if they will forgive me, of the case
of Faye, whose experience was so brilliantly articulated in
the Daily Mail on 2 May. At the age of 27, Faye was
diagnosed with crippling rheumatoid arthritis. She
describes the side-effects of conventional drugs as,
“more disruptive to daily life than the disease itself”,
which is saying something with rheumatoid arthritis. Faye
recognised that prescribed drugs are fine for some people,
but not for her. Having never used an illegal drug, and
rather fearful, she found cannabis, and very slowly came
off her prescribed medications. What was the result? She
stopped feeling sick all the time—imagine a life of feeling
sick all of the time. Now, two and a half years later,
taking only cannabis, Faye says that her quality of life is
now 98% of what it was before the diagnosis. She works
full-time. Not only is this absolutely wonderful for Faye
but it is saving the NHS thousands of pounds a year in
medications, consultant appointments, GP appointments and
so forth.
Under our drug schedules, as all noble Lords in this Room
know, cannabis is listed as a dangerous drug with no
medicinal value. In reality, of course, cannabis is safer
than many prescribed medications and there is growing
evidence of its medicinal value for a remarkable list of
conditions. Our schedule is simply wrong and should not
remain as it is. We need to inject some urgency into the
situation. It is unnecessary and in my view cruel for these
patients to suffer another two, three or even more years of
agonising, sleepless nights and pain-stricken days or risk
arrest to get hold of cannabis, which they tell us is the
only effective medication with minimal or no side-effects.
For the first time, the UN is on our side and on the side
of our Government should they wish to undertake some
reform. The United Nations Office on Drugs and Crime—the
UNODC—at the UN General Assembly Special Session on Drug
Policy in April last year, made it clear that
evidence-based public health policy is here to stay, and
that treatment without stigma should be the driver of drug
policy. This was a most important statement from the UN
body at the centre of international drug policy. After 60
years of drug policy dominated by the notion of a “war on
drugs” and the ludicrous aim of creating a drug-free world,
the UN is at last asking member states to consider a
pragmatic, realistic approach. From now on, countries need
clear objectives—how remarkable: let us have some
objectives—such as reducing addiction and harm in the
consumer countries, and reducing violence and corruption in
the producer and transit countries.
If the world is to follow the UNODC lead, countries need to
evaluate policies and introduce those for which there is an
evidence base. This brings us directly back to medicinal
cannabis. We have sufficient evidence worldwide to know
that cannabis has very significant medical properties. As I
have said, we can no longer justify its Schedule 1 status.
At its last meeting, the World Health Organization’s expert
group agreed that the widespread acceptance of medicinal
cannabis means that the WHO’s insistence on its having no
medicinal value appears incongruent, particularly as it
relies on 80 year-old data. I believe that is actually
progress.
Our own Medicines and Healthcare products Regulatory
Agency, the MHRA, determined last October that products
containing cannabidiol—CBD, a derivative of cannabis—are
indeed medicines and can be prescribed. How can we say
under Schedule 1 that cannabis has no medicinal value when,
according to our regulatory body, a part of it does? We
cannot. We are fortunate to have Ministers in the Home
Office who understand the evidence. A blog by the Home
Office Minister in April stated that the
Government’s view is that cannabis should be subject to
“the same regulatory framework” as other potential
medicines, subject to approval from the MHRA.
The big question—this is very important—is whether the MHRA
can accept a special status for cannabis, an inexpensive
weed with such valuable medical properties. If cannabis is
put through five or 10 years of double-blind random
controlled trials, it will finish up so expensive that it
will be ruled out from the NHS by NICE. Sativex is a good
example. My fear is that Epidiolex, for children with
specific strains of severe epilepsy, may also be priced out
of the NHS market in another three years’ time when the
lengthy trials finally come to an end. It is impossible to
overestimate the urgency of treatment for these epileptic
children, who suffer severe brain damage with hundreds of
seizures every single day. Their brains are being destroyed
and that damage will not be reversed.
Another tragedy that we really need to think about in
relation to Epidiolex is, I understand, that GW
Pharmaceuticals, which has spent £20 million on these
trials, now realises that another cannabinoid would be more
effective for these children with severe epilepsy than the
cannabinoid upon which those £20 million-worth of trials
were based. It cannot repeat them all, so a suboptimal
medicine will be put to the MHRA for approval. There is
something terribly wrong here and I would be grateful if
the Minister would meet me to talk about the need to
consider a safe—it must be safe—but less costly process of
trials for cannabis medicines than is required at present.
Columbia Care, a well-respected company providing reliable,
dosable cannabis, may provide an answer. Its products are
superior to those accepted in the Netherlands and Germany
and may provide a model of trials acceptable to the MHRA.
There are other reputable companies providing good-quality
cannabis products to Israel and elsewhere. Already 28 US
states, 11 European countries and the whole of Latin
America recognise that cannabis is a medicine. More states
and countries join that list every year. The illegal status
of cannabis has undoubtedly discouraged research into its
medicinal properties. Oxford University, however, will be
funded to the tune of £10 million by Kingsley Capital
Partners to investigate our own endocannabinoid system. It
is our own system that explains the extraordinary powers of
cannabis. I will not go into this but in the meantime
Professor Mike Barnes’s report, commissioned by our APPG
for Drug Policy Reform, has reviewed all the international
data and showed beyond doubt that cannabis is indeed an
effective medicine for a number of conditions.
In conclusion, I appeal to the Minister to request the
ACMD, under the leadership of its excellent chair, Dr Owen
Bowden-Jones, to review the evidence for the Schedule 1
status of cannabis and to make recommendations as soon as
possible. The UK will then be prepared to respond quickly
to the WHO review. I hope that the ACMD will consider the
regulations we would need to support a revision of the
cannabis schedule. Obviously, a good set of regulations
would be extremely important. Again, I hope the Minister
will respond to the urgency of the need for reform for
these patients.
4.09 pm
-
(Con)
My Lords, in a civilised society, one of the ways by which
we are judged is how we look after those who are
disadvantaged through no fault of their own: the young, the
old, the infirm and the weak. Among them are those who have
a particular condition or disability that cannot easily be
remedied by orthodox medical care or modern drugs. But if
we cannot help them conventionally, nor should we prohibit
them from accessing less mainstream treatments if they
believe that those treatments can alleviate some of their
discomfort or pain. We all know why cannabis is illegal,
and whether or not we agree with its prohibition—your
Lordships will know that I never have—we can recognise the
good motives of those who introduced that legislation and
prohibited its use almost half a century ago. That happened
some years after the proposal to ban heroin and cocaine was
dropped by the Home Office. The Minister responsible
agreed, after meetings with doctors’ representatives, to
permit those drugs to be categorised as controlled rather
than prohibited drugs so that even though they were
recognised as dangerous and addictive, they could be
prescribed by doctors because of their unique therapeutic
value. I know a little about that because my own father was
the Minister responsible for doing that in the post that my
noble friend holds in the Home Office today.
At that time, no such therapeutic benefit was attributed to
cannabis, which is why it was banned. Now we know
differently. We live in an age of evidence-based policy, as
the noble Baroness said. However, while there is scientific
research that demonstrates the value of cannabis, such as
that undertaken by Professor Raphael Mechoulam at the
Hebrew University in Jerusalem, perhaps more importantly
there is overwhelming anecdotal evidence from many
individuals, some of whom I too have met personally, that
their symptoms can be alleviated by cannabis. We would be
negligent and, as the noble Baroness said, cruel to ignore
that evidence.
I hope my noble friend will not seek to resist the proposal
of the noble Baroness, Lady Meacher, by advocating a long
and complex process of drug trials. This is unnecessary. In
November 2015, scientists in the United States announced
the discovery of a drug that cures, without any side
effects, hepatitis C—until then, incurable, untreatable and
usually terminal. Some 300,000 people in Britain have it
today. In less than three years, without any extensive
trials, thousands of patients throughout the world, who
until then faced an uncertain future, has been completely
cured of hepatitis C because of the use of this drug. I
have a slight interest in it because I am one of those who
has been cured within the last six months, and I am
immensely grateful to NICE for the decision it made to
allow the prescription of this drug without any of the
requirements to go through the usual years of testing
required by the MHRA. So it can be done and it has been
done.
Whatever regime Parliament puts in place will inevitably be
circumvented by those who want to do so. Alcohol, tobacco
and opiates are all controlled in different ways by the law
but they are all abused in a way that the law does not
permit. One cannot stop that. Arguably, the drugs that are
most abused and cause the most harm are those that are
routinely and quite legally prescribed by thousands of
doctors, who should know better. So the argument that
cannabis is uniquely dangerous and capable of being abused
is not credible and appears simply obstructive for the sake
of it. Let us therefore have no humbug today. Rather than
looking for excuses to do nothing by citing spurious
reasons from a bygone age, and thus needlessly prolonging
the suffering of patients whose lives could be immeasurably
improved, I hope my noble friend will use this debate and
opportunity to make this tiny, reasonable and unique
move—at no disadvantage to the taxpayer—and show the world
that we are the civilised nation that we aspire to be.
4.13 pm
-
(Lab)
My Lords, the noble Baroness, Lady Meacher, has laid out
the case admirably and I support her appeal to the
Minister. I will simply tell the Committee about the
experience of one person which illustrates how lamentable
are the consequences of the present confusion in government
policy and the Government’s refusal to remove obstacles to
making cannabis-based medication available on prescription
in this country beyond the extremely limited basis that now
applies.
The person I shall refer to as TW got in touch with me to
tell me about her situation. She suffers from advanced
degeneration of the lumbar and cervical spine and she
experiences chronic neuropathic back and leg pain. It is
tough, not just for her but for her husband and children.
Over the last 15 years, she has been prescribed some 35
different medications: anti-nausea, antispasmodic,
anti-inflammatory and antidepressant medications. At one
point she was on the equivalent of 180 milligrams of
morphine a day. She has had caudal and facet joint
injections. In 2015, she underwent major surgery, which
most unfortunately has left her in yet greater pain and
disability.
However, TW has been able to come off these high-dose
morphine-based medicines and all her other medications,
with their horrible side effects, because she has been
prescribed, privately, Bedrocan. The active ingredient in
Bedrocan is dronabinol, derived from cannabis. Bedrocan is
not licensed in this country, though it is in Holland,
Finland, Germany, Switzerland and Italy. TW has a letter
from Her Majesty’s Customs informing her that she is
legally permitted to bring Bedrocan, as prescribed for her
personal use, into Britain from Holland. If Sativex, also
derived from cannabis, were suitable for her she could, on
the other hand, legally collect it on prescription from her
local pharmacy. She was previously prescribed morphine, an
opioid in same class as heroin and far more dangerous than
cannabis, and then Fentanyl, of terrifying power, as we see
in the crisis of opioid addiction in the United States of
America. Both were on NHS prescription, and she was able to
collect those prescriptions from her pharmacy. Yet, as a
patient for whom no other medication is effective to
relieve her chronic pain without unbearable side effects,
TW has to endure an arduous, painful, exhausting and costly
journey in her wheelchair, four times a year, to collect
her prescription of Bedrocan from a Dutch pharmacy. She
very reasonably asks how this can be reasonable.
Cannabis, absurdly, is in Schedule 1, the schedule for
controlled drugs deemed to be of no medicinal value.
Bedrocan, cannabis-based, is in Schedule 2, the same
schedule as morphine, diamorphine—which is heroin—and
Fentanyl. Sativex is in Schedule 4. The scheduling is a
mess. For the Home Office and the Department of Health
between them to force TW and others like her to go to
Holland to obtain the only medication that is truly
effective for them is to taunt them in their suffering. We
should do better, and I look forward to the Minister
explaining how the Government will do so.
4.17 pm
-
(LD)
My Lords, I congratulate the noble Baroness on this debate
and the all-party group on its work and the excellent
report that was published on this subject. I need to warn
my noble colleague next to me, the noble Lord, , that I am going to be
very short in my contribution. I put my name down for this
debate because I did a little bit of background research
again, and the thing that really came over me was the
Government’s own 2017 drug strategy. It is an excellent
document, which states:
“In 2015-16, around 2.7 million ... 16-59 year olds”—
so on the whole, as Members of the House of Lords, we are
not included in this—
“in England and Wales reported using a drug in the last
year”.
It is estimated that just over 2 million of those were
cannabis users. Of course, included in that are a number of
people who had to use cannabis as a medicinal aid for their
suffering.
I was also interested to look up the information—asked for
by my former right honourable friend, —that only about 2,000
people are actually arrested over cannabis. The message
that this put over to me was that those people who need
cannabis as a medicine to help their suffering have to go
down an illegal route so that they can either be healed or
get help with their suffering. But this is something that
the majority of recreational users do not even have to
worry about, because the chances of their being arrested or
prosecuted are very low indeed. Yet—for all the illogical
reasons already given around how other drugs are treated—we
demand that the people requiring this degree of assistance
from this particular drug have to commit criminal acts
themselves to alleviate their suffering. It is crazy and I
hope this debate will be a part of stopping the very
illogical and cruel situation that we put those users in.
4.20 pm
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of Dalston (CB)
My Lords, I echo the congratulations offered by the noble
Lord, , to the noble Baroness,
Lady Meacher, on securing this debate and for all her
tireless work to secure a more rational policy on the
regulation of drugs, from founding the all-party group,
whose reports we have been reading, to her work and
representations at the United Nations and around the world.
The noble Baroness, in encouraging me to speak this
afternoon, said that it need only be a very short speech.
With the time limits, I think we have no option but to make
a very short speech.
I declare an interest: I am a member of the aforementioned
all-party group, but I was not involved in the inquiry into
the medicinal use of cannabis. Cannabis, as we have heard,
is classified with dangerous drugs with no medicinal value,
yet it is clear that it does have medicinal value. It was
perceived to provide great relief by 86% of those
responding to an online survey commissioned by the
all-party group. More than 90% reported no or only mild
side-effects, whereas—as we just heard from the noble Lord,
Lord Howarth—respondents using prescription medicines can
experience considerable side-effects. The evidence is
nuanced as to the precise scope of the medicinal value, but
the Barnes review undertaken for the all-party group
concluded that there is good evidence for the efficacy of
cannabis in the management of chronic pain and the
side-effects of chemotherapy.
At the very least, therefore, cannabis-based treatment can
provide significant benefit for a group of patients of at
least 10,000—and, in some estimations, very many
more—suffering from chronic pain where other treatments
have failed. This would be reason enough to reclassify
cannabis. Schedules 2 and 3 include drugs that may be
illegal for recreational use but can be made available on
prescription. If cannabis were to be placed in Schedule 2,
it would be in the same class as heroin, which is no less
addictive—indeed, it is considerably more so, as we
know—and there is no evidence of significant diversion of
heroin from medical supplies to the illicit recreational
market. Moreover, as we again heard from the noble Lord,
Lord Howarth, Sativex, which is a proprietary product
derived from cannabis, is classified in Schedule 4. In
these circumstances, retaining cannabis in Schedule 1 is
illogical and perverse.
The overriding reason for moving cannabis to one of the
other schedules—this is my main point, really—is that it
follows of regulation rather than prohibition. In the
reading that I did in preparation for this debate, I
counted that this has at least six consequential
advantages, but I have time to mention only a couple of
them. First, since the use of cannabis would now be lawful,
patients could take it under medical guidance and
supervision. When that guidance and supervision is not
available, when people are forced to acquire their cannabis
outside the law, the product that they obtain off the
street is often much more harmful. How much better to be
using it when it provides its benefits under proper medical
supervision.
Secondly, the current regime places a stranglehold on
research. Carrying out research into cannabis in the UK has
been described as a costly obstacle course. It involves a
minimum outlay of £5,000 to cover licensing and security,
and licence applications can take as long as a year. It has
been calculated that research involving Schedule 1 drugs
takes significantly longer and costs about 10 times as much
as research into other drugs.
In view of all the considerations that have been spoken to
in the debate, I hope very much that the Minister will
agree that the matter should be referred to the advisory
council. Referring the matter for the opinion of an
independent expert body, which of course does not commit
the Government, is not exactly selling the pass.
4.25 pm
-
(Con)
My Lords, I too congratulate the noble Baroness, Lady
Meacher, on raising this issue and on the way in which she
has done it. The Question asks whether the Government “plan
to invite” a review of the evidence. It is asking not
whether the Government will reschedule cannabis but whether
they plan to review the evidence, or at least to have the
evidence reviewed. That is the crucial point.
It is six and a half years since I tabled a QSD in which I
asked what consideration the Government had given,
“to establishing a royal commission on the law governing
drug use and possession”.
I argued the case for evidence-based policy. My starting
point was that there was a demonstrable problem and that we
needed to address it. I was not advocating that the policy
should be adopted but making the case for reviewing
existing policy. In reply, the Minister said that there was
considerable disagreement on the issue—well, not in that
debate; every Peer who spoke, bar the Minister, agreed with
me.
In this debate the focus is on the rescheduling of
cannabis. As we have heard, there is a particularly
powerful case for reviewing the use of cannabis under
certain conditions for medicinal use. The MS Society has
changed its position on the use of cannabis for medicinal
purposes in the light of reviewing the evidence, and its
stance is a measured one.
The arguments that have been deployed against change by the
Home Office do not stack up, especially under a
Conservative Government. If a law is not working and change
is resisted on the grounds of sending the wrong signals,
then Ministers have little grasp of the Conservative view
of law.
I repeat what I said in 2011:
“My case is that we need to explore whether the present law
is necessary and sufficient, whether it is necessary but
not sufficient, or whether it is neither necessary nor
sufficient”.—[Official Report, 9/3/11; col. 1675.]
Implicitly the Government took, and take, the first of
those positions. There was and is no critical reflection.
Yesterday my noble friend Lady Williams reiterated that she
supported evidence-based policy. Now is the time to
consider the evidence. Will my noble friend commit to that?
4.27 pm
-
(Lab)
My Lords, I thank the noble Baroness, Lady Meacher, for
initiating this debate. I just want to say something about
the case of a little boy. I think that some of us have
heard from his grandmother but I shall explain the case
briefly.
He has a very rare condition—which I think is called
non-inherited genetic mutation in the PCDH19 gene—for which
so far only a steroid treatment is effective. This is not
suitable for long-term use because of the serious health
consequences. It is very likely that whole-plant medical
cannabis will work and will be without particular
side-effects. To get such medical cannabis, the family of
the six-year-old boy would have to travel to a country
where it is legal for doctors to prescribe medical
cannabis. There is a product under test called Epidiolex.
It is a cannabis-based product but is not yet available and
is subject to a long testing regime, which may be too long
for this little boy. There is a need to move quickly to
permit medical cannabis to be given to this little boy
under medical management.
I now turn to the wider issue of cannabis for people with
MS. I should declare an interest in that a member of my
family has MS. We have had an excellent briefing from the
MS Society, which says that 22% of people with MS have
tried cannabis. I only know that a consultant thinks that
every one of his patients has tried cannabis, not 22% of
them, and I put that to the MS Society.
There is a product called Sativex that might do the
business but which is not available to NHS patients,
although it should be in Wales. The problem is that there
is a dangerous version of cannabis known as skunk. People
who are buying it on the illegal market are liable to get
skunk, which I understand is not desirable, whereas
ordinary cannabis is okay. By making the whole thing
illegal, we are encouraging people to go to dealers, who
are liable to give them the dangerous stuff rather than the
helpful stuff.
Some doctors say that there is no evidence that cannabis is
helpful to people with MS. I have a simple answer to that.
If a person suffering from a medical condition like MS
feels that cannabis is helpful, surely that is enough
evidence. I am not anti-scientific and I understand the
noble Lord’s comments, but if a patient feels that it is
helpful, then by definition it must be. That is the case
for me.
4.30 pm
-
(Con)
My Lords, I thank the noble Baroness for getting us this
debate and for the work that she has done for the APPG,
which has produced a compelling evidence base for policy
change. She spoke of the striking evidence of dramatic
improvement to their health that some cannabis users have
experienced. That, combined with the failure of
prescription medicines to relieve their symptoms, has
caused patients to try herbal cannabis even though access
to it is not lawful. Estimates as to the use of medicinal
cannabis suggest that 30,000 patients in this country are
using it, most of it coming from illegal street sources.
Also striking is the evidence that a majority of users have
discussed using a cannabis treatment with their GP or
consultant. Whether or not cannabis is legalised, the gain
from having a regulated system that does not put both
patients and their medical advisers in an intolerable
position and vulnerable to the dangers of using street
supplies of drugs is compelling.
The background to this debate is HM Government’s 2017 drug
strategy, which was published in July. That strategy, which
apparently is to be delivered by a board chaired by the
Home Secretary, is about abuse and harm. There is no
mention of medicinal cannabis. The ACMG has a central role
in this. The council, emphasising the health significance
of the use of cannabis, has made recommendations for
further research. The Motion asks that that research should
be extended, but because the evidence produced by the APPG
shows clearly that the Schedule 1 listing makes research
into the use of cannabis-related drugs and drug trials
difficult and expensive, there is a problem ahead.
Ministers claim that a clear regime is in place to enable
drugs that contain cannabis to be developed and licensed,
but they can cite only one example, that of Sativex.
Because of the difficulties and costs of applying for a
licence, no application has been made in respect of herbal
cannabis.
The Medicines and Healthcare products Regulation Agency has
stated that products containing cannabis are medicines.
Surely that conclusion and the legalisation of medicinal
cannabis in so many countries combined with much evidence
that it has not caused an increase in crime, abuse and harm
in those countries—probably the reverse is true—provides
powerful reasons for the Government to reconsider their
policy and look at possible models for regulation. This is
a health issue and I really wonder whether the Department
of Health should not play a larger role in policy-making,
which in my view is too dominated by the Home Office.
4.34 pm
-
(CB)
My Lords, I too congratulate the noble Baroness, Lady
Meacher. I want briefly to look at the body of evidence
from overseas which clearly demonstrates that a more
sensitive and targeted approach to the use of cannabinoids
can bring positive results. In the USA, those states which
have medical marijuana laws see lower rates of opiate
overdose.
A recent study indicates a much lower use of opiates by
pain sufferers using cannabis as treatment. This year a
study has shown a reduced incidence of opioid-related
hospitalisations in those states and according to the world
health rankings the current drug-related death rate, mainly
caused by opiate use, for the UK is 3.83 per 100,000. This
compares to the Netherlands, which has the most-established
scheme for medicinal cannabis in Europe, of 0.63. This
means that the UK has a rate for drug-related deaths more
than six times higher than that of the Netherlands. Does
the Minister have any comment on these figures, or on the
letter, published in the Lancet this June, from Dr David
Nutt of Imperial? He notes that in his view the UK
Government, on the advice of the Advisory Council on the
Misuse of Drugs, made two problematic changes to the UK
drug control regulations of the Misuse of Drugs Act 1971.
First, they put into effect new very wide-ranging bans
against a whole range of synthetic cannabinoids and,
secondly, they rejected an appeal by senior UK scientists
to remove THCV from Schedule 1, the highest level of
control in the Act. Both decisions have substantial impacts
on the UK’s research communities.
To make these drugs illegal and prevent others replacing
them, the ACMD recommended that the whole chemical series
be banned. However, many of this now illegal series are
contained in current medicines and to get around this
problem the Home Office exempted these and seven other
medicines that would otherwise have become illegal. This
exemption-based approach has, unfortunately, a fatal flaw:
most, if not all, these drugs were derived from a chemical
series that contain precursors from which other medicines
might be developed. Now these are illegal, and anyone
caught supplying them is liable to up to 14 years in
prison. These potential penalties will have a chilling,
possibly fatal impact on pharmaceutical drug discovery in
the UK, because complying with the regulations adds a vast
cost burden to the pharmacology industry and to academic
researchers. Dr Nutt found it concerning that the
pharmaceutical experts on the ACMD did not appear to
foresee this problem. Worse, it appears that the new
regulations were not subject to proper consultation with
the academic research community and the pharmaceutical
industry.
History suggests that earlier bans on synthetic
cannabinoids had little effect on their use. I fear it is
likely that this new law could fail in its primary
objective and badly damage UK research.
4.37 pm
-
(Con)
My Lords, I congratulate the noble Baroness, Lady Meacher,
on securing this debate and I apologise for not having
applied to speak originally—I was not expecting to be able
to be present. I echo everything that has been said in this
debate and I do so as a diagnosed MS sufferer. I have been
confronted by the diagnosis; as it happens, contrary to
what the noble Lord, , said, I have not taken
cannabis at any point, but I agree with his overall
analysis that on most estimates the figures are gross
underestimates of the number of people who have taken
cannabis as a treatment for my illness and, I believe, for
many others as well. So I support everything that has been
said around the Room this afternoon.
4.38 pm
-
(LD)
My Lords, I strongly support the campaign of the noble
Baroness, Lady Meacher, to make medicinal cannabis
available legally for patients who can be helped by it and
I congratulate her once again on her persistence. While the
noble Baroness, Lady Williams, is very welcome in her place
today, I agree with the noble Lord, , that we should
be seeing a health Minister responding to a debate of this
nature—so does she, I think. The lack of availability of
this medicine for thousands of people in pain is just one
of the terrible consequences of a failure over the years by
the Government to see that their policies are not working.
Their stubborn persistence with a set of policies that are
manifestly failing is extraordinary. If any other policy
were as much of a failure as the Government’s drugs policy,
they would drop it like a hot potato.
The current classification of drugs is meant to avoid their
misuse but fails completely to do so. On top of that, it
penalises people for whom cannabis can be a lifesaver. They
and their clinicians are forced to resort to powerful drugs
such as morphine to alleviate pain because cannabis has
become caught up in the debate on recreational drugs.
Let us take the case of five year-old Alfie Dingley,
mentioned by the noble Lord, . Alfie has life-threatening
seizures. The drugs being used to treat him at the moment
are frequent, intravenous steroids which could shorten his
life, cause him to develop cancer, damage major organs or
even induce psychosis. All other treatments have failed and
his parents and grandparents live in constant fear of his
next, possibly fatal seizure. Yet in Holland, where the law
on cannabis is more rational and compassionate, doctors are
able to treat children such as Alfie successfully.
In the Republic of Ireland, a named practitioner can be
licensed to prescribe cannabis for medicinal purposes to a
named patient. A number of other countries do something
similar, so why can we not do that here? Can we not have a
trial in this country to look at how children such as Alfie
can be helped under proper medical supervision? Given that
Alfie, along with many of the other patients we have heard
about, has been given many other powerful drugs, some of
which are not licensed for children as young as him, surely
the risks of allowing him legal access to cannabis are
considerably less? Yet to obtain cannabis legally, as we
have heard is the case with other patients, Alfie’s parents
would have to travel abroad at their own expense.
Ironically, Alfie’s UK consultant would be willing to
prescribe cannabis but is not allowed to do so.
Rescheduling cannabis, as the noble Baroness, Lady Meacher,
has suggested, would allow that to happen.
I and my colleagues heard from many patients in the noble
Baroness’s commission when considering the matter. The
evidence was very compelling. Today, your Lordships have
called on the Government to base their policy on evidence,
not misguided prejudice. The Government should hear the
voices of the thousands of generally law-abiding patients
who are forced to break the law or go to enormous trouble
and expense to travel abroad to get the medicine that they
know works for them. Those people do not want to have to do
that, and there are thousands more who could benefit but
are not prepared to take the risk. Why are we putting good
people in this invidious situation? It is cruel, it is
illogical and it is time that the Government did something
about it.
4.41 pm
-
(Lab)
My Lords, I first apologise for being late for the
beginning of the debate. If I had a credible excuse, I
would offer it. I congratulate the noble Baroness, Lady
Meacher, on securing the debate, which has attracted a lot
of interest—as reflected by the number of speakers.
As has been said, there is a regime in place, administered
by the Medicines and Healthcare products Regulatory
Agency—MHRA—to enable medicines, including those containing
controlled drugs such as cannabis, to be developed,
licensed and made available for medicinal use to patients
in the UK. However, as has been said, and as I understand
it, only one product containing cannabis
extracts—Sativex—has been licensed as a medicinal product
by the MHRA. Equally, as I understand it, the MHRA has
recently decided that CBD-only products—cannabidiol is one
of the main compounds of cannabis—which are used to treat
various symptoms, should be considered as medicines.
The question we are debating is whether the Government plan
to invite the Advisory Council on the Misuse of Drugs to
review the evidence supporting the rescheduling of cannabis
to Schedule 2 or Schedule 4. Cannabis is controlled as a
class B drug under the Misuse of Drugs Act 1971. In its raw
form, it currently has no recognised medicinal benefits in
the UK and is therefore listed as a Schedule 1 drug under
the misuse of drugs regulations. This explicitly forbids
doctors from prescribing cannabis and inhibits research.
If cannabis were rescheduled, it would enable patients with
a wide range of conditions to obtain cannabis medicines to
alleviate their symptoms, and doctors could prescribe it on
a named patient basis, taking responsibility for patient
safety, until licensed cannabis medications became
available.
In their 2017 drugs strategy, the Government said that they
were committed to grounding their approach in the latest
available evidence. They stated:
“The advice of the Advisory Council on the Misuse of Drugs
… is fundamental to informing our approach and we will
continue to seek their valuable input and advice”.
Have the advisory council expressed any view to the
Government that it now thinks it appropriate to undertake a
review into either the classification or the rescheduling
of cannabis—and, if so, what has been the Government’s
response? If significant new evidence is now available that
was not available previously and which might well influence
the view of the advisory council—which appears to be the
position—there is a case for inviting it to consider it,
particularly in the light of the Government’s position that
the advice of the council is fundamental to forming their
approach.
We have heard in the debate about the case of Alfie, who is
nearly six. As I understand it, some children with his
condition have responded well to whole-plant medical
cannabis with no side-effects. Indeed, as I understand it,
Alfie’s consultant at his children’s hospital supports
trying medical cannabis but cannot do so because it would
be illegal for him to prescribe it at present. As has
already been pointed out, in several other countries,
including Ireland, a named consultant can prescribe
whole-plant medical cannabis to a named patient. The future
does not look good for Alfie at present. I ask the Minister
to look at Alfie’s case to see what help can be given to
get medical cannabis under the management of his consultant
here—either now or, if he has to go abroad for such
treatment, once it has been shown that it helps him.
4.46 pm
-
The Minister of State, Home Office (Baroness Williams of
Trafford) (Con)
My Lords, first, I also declare an interest in MS. As the
noble Lord, , knows, I worked with MS
patients for many years before I got involved in politics—I
do not know quite how I made the transition, but that was the
case. Some of the noble Lord’s anecdotes from patients chime
with things that I heard. I know that there is significant
feeling in the House on this issue. It is also clear from
noble Lords’ remarks that they are keen that government
policy on this issue should be led by evidence—as my noble
friend said, I confirmed
that yesterday—but also should not prevent patients from
obtaining relief from symptoms using effective medicines.
As the noble Baroness, Lady Meacher, said, the WHO’s Expert
Committee on Drug Dependence has committed to reviewing the
scheduling of cannabis under the UN’s 1961 convention. The
review will consider therapeutic use as well as dependence,
and the abuse potential of several constituent parts of
cannabis, including the cannabis plant itself and cannabis
resin, cannabidiol, or CBD, THC, isomers of THC and, extracts
and tinctures of cannabis. The review is due to conclude by
early 2019 and I, like most people here today, am very
interested in its outcome and look forward to future
opportunities to debate this issue—as I know we will—as and
when the WHO concludes its work. I must add that the
recognition of CBD as having medicinal application
necessarily means that the other constituent parts will do so
as well. Each compound ought to be assessed on its merits.
As noble Lords have said, cannabis in its raw herbal form
continues to be listed in Schedule 1 to the Misuse of Drugs
Regulations 2001 as a substance with no recognised benefits
in the UK, but I must underline that this is in its raw form.
The system of scheduling does not preclude medicines based on
cannabis from being developed. The Misuse of Drugs Act 1971
regime, along with the associated regulations, enables the
availability of controlled drugs which have recognised
medicinal uses in UK healthcare—of which there are many.
We are already able to rely on a process, administered by the
Medicines and Healthcare products Regulatory Agency, MHRA, in
parallel with the Home Office’s licensing system, to enable
medicines, including those containing controlled drugs such
as cannabis, to be developed, licensed and made available for
medicinal use to patients in the UK. In the case of a
Schedule 1 drug such as cannabis, the Home Office is willing
to consider applications for research licences to facilitate
the development of new medicines, as long as the appropriate
ethical approvals have been given, as we have done in the
past. I am very happy to meet again with the noble Baroness,
Lady Meacher, as we do regularly, to discuss this issue.
In the case of the cannabis-based drug Sativex, the
Government have, as noble Lords have said, placed the product
in Schedule 4 of the Misuse of Drugs Regulations to allow it
to be legally supplied on prescription. Sativex was granted a
marketing authorisation by the MHRA and was rigorously tested
for its safety and efficacy before receiving approval for
this application. This rigour should equally be applied to
future medicinal products containing cannabis.
As has also been pointed out today, the MHRA has offered an
opinion that products containing CBD, when used for a medical
purpose, should be regulated as medicinal products. A CBD or
cannabidiol product in its pure form is not controlled under
the Misuse of Drugs Act 1971, so where it can be extracted
and isolated from the controlled substances in cannabis it
would not require a licence from the Home Office. However, a
CBD product that contains any trace of psychoactive compounds
that are found in cannabis, such as THC or
tetrahydrocannabinol, is considered to be a controlled
substance under the 1971 Act and therefore unlawful to
possess and supply unless it fits the criteria for an exempt
product under the Misuse of Drugs Regulations 2001. The MHRA
is working with individual companies and trade bodies to make
sure that products containing CBD used for a medical purpose
which can be classified as medicines satisfy the requirements
of the Human Medicines Regulations 2012.
We continue to facilitate forward-looking research involving
cannabis and cannabinoids. There were 19 cannabinoid clinical
trial authorisations granted between 2005 and 2015. These
trials cover MS, dental applications, psychotic disorders,
addiction to cannabis, type 2 diabetes, epilepsy, interaction
with other medicines and brain diseases. Research in this
area is ongoing.
The noble Baroness, Lady Greengross, asked about research
into synthetic cannabinoid changes. I know that my right
honourable friend the Home Secretary has commissioned the
ACMD to look into whether there are barriers to research into
Schedule 1 drugs as a result of changes to synthetic
cannabinoid generic legislation. The Home Secretary has asked
the council to provide its advice before the end of this
year.
The noble Baroness, Lady Meacher, and the noble Lord,
, asked about Epidiolex. Our
position on it is that, as for any other medicine and as we
did with Sativex, it must be put through the same stringent
process to ensure its safety and efficacy, for the benefit of
patients.
My noble friend suggested that
the Department of Health and not the Home Office should be
responsible for this. I quietly nodded there. Like the
previous strategy, the 2017 drug strategy takes a
cross-government approach that reflects the need for
co-ordinated action to tackle the problem in all its
dimensions. Given the strong link between drug use and
offending, the Home Office has and will continue to provide
the governance and accountability essential to the effective
delivery of this cross-departmental approach. The Department
of Health leads on the building recovery strand of the
strategy and, together with the Home Office, leads on the
reducing demand strategy, along with Public Health England.
To ensure that we are doing all we can—and following my
meeting with the noble Baroness, Lady Meacher—I have recently
written to my noble friend Lord O’Shaughnessy, who is the
Minister for Health in your Lordships’ House, to consider how
the Government can facilitate the development and
availability of cannabis-based medicines such as Sativex.
We are open to the development of new products based on
cannabis and look forward to the review from the WHO’s expert
committee. I am sure that the ACMD will follow its
conclusions with great interest.
-
The Minister has not made any mention of Bedrocan in her
response to the debate. Does she think it reasonable that TW,
in the circumstances I described, has to make these visits to
Holland to collect her medication, which has been prescribed
for her in Britain but which she is not permitted to obtain
from her local pharmacy? Is that a reasonable state of
affairs and if the Minister thinks it is, why? If she thinks
it is not, what will the Government do?
-
I noted the noble Lord’s mention of Bedrocan. I had not heard
of it and I am very willing to look into that specific drug.
There are of course many drugs available in other parts of
the world that are not necessarily available here and vice
versa. I will write to him on that point. I will also take up
the point about Alfie separately.
-
May I thank everybody who has spoken so effectively in this
debate? So many powerful points were made and we have managed
to avoid duplication, amazingly. It just shows how many
points one needs to make in relation to this—
-
(Con)
My Lords, there is no right of reply in this debate.
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