Organisations invited to apply for funding for reducing the use of animals in research
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Organisations can apply for a share of £2 million to tackle 3
challenges that help to replace, refine or reduce use of animals in
research. There are 3 challenges each seeking alternatives to using
animals in experiments. The National Centre for the
Replacement, Refinement and Reduction of Animals in...Request free trial
Organisations can apply for a share of £2 million to tackle 3 challenges that help to replace, refine or reduce use of animals in research.
There are 3 challenges each seeking alternatives to using
animals in experiments.
The National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs) and its sponsors have £2 million to invest in a series of challenges to reduce the use of animals in experiments. NC3Rs is an independent scientific organisation that supports UK scientists in finding ways to replace, reduce or refine the use of animals in research. Its CRACK IT programme invites small and medium-sized businesses and researchers to find solutions to specific challenges. These 3 challenges are co-funded by the Engineering and Physical Sciences Research Council, with contributions in kind by Galvani Bioelectronics, GSK, MRC Harwell Institute and Sanofi Pasteur EU. This funding competition is being delivered by Innovate UK through SBRI (the Small Business Research Initiative). 2018 CRACK IT challengesSingle or 2 phasesThe challenges are run in either a single phase or 2 phases. Single-phase challenges involve less research and mainly focus on the validation of new technologies. Two-phase challenges require significant funding and can include research, development and validation of new technologies. ImmuLiverThe aim of this 2-phase challenge is to develop an in vitro model of the human liver for assessment of yellow fever vaccine. Current yellow fever vaccines are assessed in macaques. Projects should overcome the lack of ‘immune competency’ in existing in vitro models. There is up to £100,000 to fund projects lasting up to 6 months in phase 1. Up to £1 million is available in phase 2 to support projects lasting up to 3 years. RaTSOne of the biggest challenges facing scientists is the imaging of affected joints in rheumatoid arthritis. Joint pain and inflammation in animal models can only be monitored indirectly by detecting the response to external stimuli. The aim of this 2-phase challenge is to develop a handheld imaging device to monitor the progression of rheumatoid arthritis in conscious rodents. There is up to £100,000 to fund projects lasting up to 6 months in phase 1. Up to £750,000 is available in phase 2 to support projects lasting up to 3 years. MoshersThis single-phase challenge aims to develop an approach or device that will accurately measure individual food intake in mice housed in groups of 3 to 5. A measurement of food intake is an indicator of general welfare and of recovery from surgery. It is also an important measurement when carrying out studies. Accurate measurement of feeding patterns is technically challenging, particularly when mice are housed in social groups. Up to £100,000 is available for projects lasting up to 1 year. Competition information
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